Always free standard shipping on all U.S. orders.
Skip to content

First-Time Buyer Special - Risk-Free Trial, Limited Time Offer!

As a first-time buyer, purchase any full-size product and receive a matching travel-size product free. If you're not satisfied with the travel size, simply return the full-size product within 30 days for a full refund, no questions asked.

The Irony of Iron

  • Iron is vital, but excess is harmful.
  • Excess iron is stored in the skin via ferritin.
  • Ferritin binds up to 4,500 iron atoms.
  • Iron lingers in skin for 60 days, far longer than skin's 26-day turnover.
  • Iron buildup increases with age.

Picture description: 3D illustration of ferritin, an iron storage protein. Ferritin stores excess iron as a mineral and releases it when needed. Acting like a sponge, it can release iron under stress, triggering oxidant formation, premature aging, and photoaging. Excess iron buildup in ferritin also alters skin tone, resembling the rusting process.

Understanding the Challenge

  • The Fenton reaction shows how iron causes oxidative skin damage.
  • Stress releases excess iron from ferritin, creating skin-aging free radicals.
  • These radicals speed up aging, photoaging, and uneven skin tone.
  • Antioxidants neutralize damage but don’t target the source—excess iron.
  • Chelation can bind free iron, but not what's stored in ferritin.

Picture description: Chemical reaction of iron oxidation by hydrogen peroxide, producing hydroxyl free radicals (•OH), known as the Fenton reaction (discovered in 1894). These potent oxidants accelerate premature aging by oxidizing biological molecules. While antioxidants neutralize the resulting oxidants, they do not address the underlying cause—iron.

Discover the Power of DII®Technology

What is DII®?

DII® stands for De-Ironizing Inducer, a breakthrough technology by Dr. Xi that removes excess iron to purify your skin.

How it works:

  • Power duo: Stabilized vitamin C + natural pearl powder tackle excess iron.
  • Vitamin C: Frees iron from ferritin, addressing oxidative damage.
  • Pearl powder: Absorbs released iron, keeping skin clear.
  • Surface protection: Shields skin from iron buildup until your next wash.
  • Long-lasting: Pearl powder’s high buffering capacity offers extended skin protection.

Picture description: Molecular mechanism of De-Ironizing Inducer (DII®) in eliminating excess iron from ferritin. DII® combines vitamin C, which releases iron from ferritin, with pearl powder (calcium carbonate), which absorbs the released iron through ion exchange. The iron is then washed away, leaving skin clean. Pearl powder’s high buffering capacity ensures long-lasting protection.

Ingredients Comparison

DII® Technology

  • First in its class in removes excess iron, the source of oxidant formation.
  • Clears harmful metals from makeup and pollution.
  • Suitable for all skin types, especially for women 35+, pregnant and midlife.
  • Proactively shields your skin before damage sets in.
  • Enhances the effectiveness of other ingredients.

Antioxidants

  • Neutralizes existing oxidants.
  • Repairs oxidative damage after it occurs.
  • Does not enhance other ingredients.
  • Repairs but doesn’t protect against future damage.
  • Common in conventional skincare products.

Chelation

  • Cosmetic chelators like green tea extract have weak iron-binding ability.
  • Only removes "free" iron, which is scarce in the skin.
  • Not strong enough to target ferritin-bound iron.
  • Its weak binding makes the effect reversible.
  • Overall, the efficacy is very limited.

Retinols

  • Accelerates the rate at which skin cells shed iron and renew.
  • Smooths skin texture and reduces fine lines.
  • Fades dark spots and evens out skin tone.
  • Can cause dryness, redness, or peeling, especially initially.
  • Increases sensitivity to UV rays, requiring consistent sun protection.

DII® Technology

  • First in its class in removes excess iron, the source of oxidant formation.
  • Clears harmful metals from makeup and pollution.
  • Suitable for all skin types, especially for women 35+, pregnant and midlife.
  • Proactively shields your skin before damage sets in.
  • Enhances the effectiveness of other ingredients.

Antioxidants

  • Neutralizes existing oxidants.
  • Repairs oxidative damage after it occurs.
  • Does not enhance other ingredients.
  • Repairs but doesn’t protect against future damage.
  • Common in conventional skincare products.

Chelation

  • Cosmetic chelators like green tea extract have weak iron-binding ability.
  • Only removes "free" iron, which is scarce in the skin.
  • Not strong enough to target ferritin-bound iron.
  • Its weak binding makes the effect reversible.
  • Overall, the efficacy is very limited.

Retinols

  • Accelerates the rate at which skin cells shed iron and renew.
  • Smooths skin texture and reduces fine lines.
  • Fades dark spots and evens out skin tone.
  • Can cause dryness, redness, or peeling, especially initially.
  • Increases sensitivity to UV rays, requiring consistent sun protection.