1894: Revolutionizing Skincare: From Fenton's Insight to i-On by Dr. Xi®

In 1894, H.J.H Fenton introduced a groundbreaking discovery: iron prompts the creation of harmful hydroxyl free radicals, sparking oxidative damage. This simple finding revolutionized our comprehension of iron's role in biology and its impact on health and disease.

Iron is essential for various biological processes, but excessive amounts can lead to oxidative stress, a condition where free radicals overpower antioxidants, causing cellular damage. Fenton revealed how iron catalyzes the formation of destructive hydroxyl radicals, a key insight known as the Fenton reaction.

The Fenton reaction occurs when iron ions, typically in the form of Fe2+, react with hydrogen peroxide (H2O2), resulting in the generation of hydroxyl radicals (OH•). This reaction can be summarized as follows:

Fe2+ + H2O2 → Fe3+ + OH• + OH-

Here, Fe2+ is oxidized to Fe3+ by hydrogen peroxide, producing hydroxyl radicals as reactive intermediates. These hydroxyl radicals can wreak havoc on cellular components, causing damage to DNA, lipids, and proteins.

Fenton's work not only advanced biological understanding but also influenced fields like environmental chemistry and medicine, particularly in diseases linked to iron overload.

However, the story doesn't stop there. Dr. Xi and his team introduced a skincare breakthrough with i-On By Dr. Xi. Using patented De-Ironizing Inducer (DII®) technology, i-On reduces Fe3+ to Fe2+ and removes it from the skin.

This innovation is transformative for skincare. By reducing Fe3 to Fe2+and subsequently removing it, i-On By Dr. Xi mitigates iron's ability to generate hydroxyl radicals, thus decreasing oxidative stress within the skin. Moreover, by removing excess iron, i-On By Dr. Xi maintains a healthy balance, preventing iron accumulation and oxidative damage over time.

The implications of i-On By Dr. Xi's discovery are profound. It offers a novel approach to combating skin aging by addressing oxidative stress at its source. By safeguarding skin cells and preserving structural components like collagen and elastin, i-On By Dr. Xi promotes healthier, more youthful skin.

In summary, H.J.H Fenton's insights laid the foundation for understanding oxidative damage, while i-On by Dr. Xi represents a significant leap forward in skincare innovation. Together, they provide a powerful arsenal in the battle against aging, ushering in a brighter future for skincare through science and innovation.

Ref: Henry John Horstman Fenton - Short Biography and Brief History Of Fenton Reagent Discovery, www.researchgate.net/publication/285872170_Henry_John_Horstman_Fenton_-_short_biography_and_brief_history_of_Fenton_Reagent_Discovery